up and at them 1. adv. phr. Actively engaged in a task as if doing combat.
"You want to know whether he will make a diligent worker?" Dick asked. "Well, I can tell you that most of the time he is up and at them like no one else I know." 2. v. phr. To become aggressively engaged in doing something; (useable as a command).
Come on, up and at them, you guys. We still have a lot of work to get done. [TahlilGaran] English Idioms Dictionary ▲